GENERAL CATALOGUE
SIK-IN-2
HY-161441 · 50 mg
MedChemExpress · Cat: HY-161441
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medchemexpress.com/sik-in-2.htmlCatalog No: HY-161441
CAS No: 3033846-20-4
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
SIK-IN-2 Compound 45 is an inhibitor for salt-inducible kinase SIK , which inhibits SKI1, SIK2 and SIK3 with IC50s of 0.1, 0.2 and 0.4 nM, respectively. SIK-IN-2 inhibits the release of TNFa with IC50 of 0.5 nM, stimulates the LPS HY-D1056 -induced IL-10 release with EC50 of 2 nM in human macrophages.