

HY-161442 · 50 mg
MedChemExpress · Cat: HY-161442
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medchemexpress.com/sik-in-3.htmlDescription
SIK-IN-3 Compound 6B is an inhibitor for salt-inducible kinase SIK , which inhibits SKI1, SIK2 and SIK3 with IC50s of 0.1, 0.3 and 0.8 nM, respectively. SIK-IN-1 inhibits the release of TNFa with IC50 of 0.6 nM, stimulates the LPS HY-D1056 -induced IL-10 release with EC50 of 3 nM in human macrophages.

