GENERAL CATALOGUE
SIK2-IN-3
HY-171590 · 50 mg
MedChemExpress · Cat: HY-171590
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Manufacturer product page
medchemexpress.com/sik2-in-3.htmlCatalog No: HY-171590
CAS No: 2810809-10-8
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
SIK2-IN-3 is an orally active SIK1/2 selective inhibitor IC50: 0.128/0.084 ?M . SIK2-IN-3 inhibits CRTC3 phosphorylation and myeloid cell pro-inflammatory cytokine production. SIK2-IN-3 ameliorates systemic and tissue inflammatory responses in a mouse anti-CD40 colitis model.
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