GENERAL CATALOGUE
SIM1
HY-141438 · 5 mg
MedChemExpress · Cat: HY-141438
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medchemexpress.com/sim1.html
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Catalog No: HY-141438
CAS No: 2719051-84-8
Category: Epigenetics
Pack Size: 5 mg
Brand: MedChemExpress
Description
SIM1 is a potent von Hippel-Lindau VHL -based trivalent PROTAC capable of degradation for all BET family members, with preference for BRD2 degradation IC50=1.1 nM; Kd=186 nM . SIM1 shows sustained anti-cancer activity.
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