GENERAL CATALOGUE
Simeprevir sodium
HY-10241A · 50 mg
MedChemExpress · Cat: HY-10241A
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medchemexpress.com/simeprevir-sodium.htmlCatalog No: HY-10241A
CAS No: 1241946-89-3
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
Simeprevir TMC435; TMC435350 sodium is an oral, potent and highly specific hepatitis C virus HCV NS3/4A protease inhibitor with a Ki of 0.36 nM. Simeprevir sodium inhibits HCV replication with an EC50 of 7.8 nM. Simeprevir sodium also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir sodium inhibits the main protease Mpro and the RNA-dependent RNA polymerase RdRp of SARS-CoV-2, and also modulates host immune responses.
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