GENERAL CATALOGUE
Simvastatin acid-d6 ammonium
HY-119695AS · 1 mg
MedChemExpress · Cat: HY-119695AS
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Catalog No: HY-119695AS
Category: Metabolic Enzyme Protease
Pack Size: 1 mg
Brand: MedChemExpress
Description
Simvastatin acid-d6 ammonium mis the deuterium labeled Simvastatin acid ammonium. Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver pKa=5.5 . Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.
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