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SIRP alpha/CD172a, His, Mouse
GENERAL CATALOGUE

SIRP alpha/CD172a, His, Mouse

Z06354 · 100 ug

GenScript · Cat: Z06354

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Catalog No: Z06354
Category: protein
Pack Size: 100 ug
Brand: GenScript

Description

Signal regulatory protein alpha SIRPalpha is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPalpha acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the don t eat me signal.Cancer cells highly expressed CD47 that activate SIRP alpha and inhibit macrophage-mediated destruction.

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