

Z06354 · 100 ug
GenScript · Cat: Z06354
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genscript.com/protein/Z06354-SIRP_alpha_CD172a_His_Mouse.htm...Description
Signal regulatory protein alpha SIRPalpha is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPalpha acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the don t eat me signal.Cancer cells highly expressed CD47 that activate SIRP alpha and inhibit macrophage-mediated destruction.
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