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Sirt1/2-IN-3
GENERAL CATALOGUE

Sirt1/2-IN-3

HY-155728 · 50 mg

MedChemExpress · Cat: HY-155728

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medchemexpress.com/sirt1-2-in-3.html
Catalog No: HY-155728
CAS No: 301313-42-8
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

Sirt1/2-IN-3 compound PS9 is a dual inhibitor of SIRT1/2 with IC50s of 1.4 ?M SIRT1 and 2.0 ?M SIRT2 , respsectivley. Sirt1/2-IN-3 completely blocks p53 deacetylation, and increase of p53 and ?-tubulin acetylation. Sirt1/2-IN-3 induces apoptosis and shows anti-proliferation activity against human leukemia cell lines.

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