GENERAL CATALOGUE
SIRT2-IN-11
HY-148408 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-148408
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medchemexpress.com/sirt2-in-11.htmlCatalog No: HY-148408
CAS No: 1005095-06-6
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SIRT2-IN-11 AEM1 is a selective SIRT2 inhibitor with an IC50 value of 18.5 ?M. SIRT2-IN-11 p53-dependently induces apoptosis, activates expression of CDKN1A, PUMA and NOXA, and increases acetylation of p53. SIRT2-IN-11 can be used for the research of p53-related cancers.
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