GENERAL CATALOGUE
SIRT6-IN-4
HY-170402 · 50 mg
MedChemExpress · Cat: HY-170402
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Manufacturer product page
medchemexpress.com/sirt6-in-4.htmlCatalog No: HY-170402
CAS No: 3075160-74-3
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
SIRT6-IN-4 Compound 10d is a selective inhibitor for SIRT6 with an IC50 of 5.68 ?M. SIRT6-IN-4 inhibits the proliferation of MCF-7 with an IC50 of 8.30 ?M. SIRT6-IN-4 arrests the cell cycle at G2/M phase, inhibits thecell migration and invasion of MCF-7, and induces apoptosis. SIRT6-IN-4 exhibits antitumor efficacy in mouse models.
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