

HY-135899 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-135899
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medchemexpress.com/sirt7-inhibitor-97491.htmlDescription
SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway..







