GENERAL CATALOGUE
Sitaxsentan sodium
HY-11103 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-11103
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Catalog No: HY-11103
CAS No: 210421-74-2
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Sitaxsentan sodium IPI 1040 sodium; TBC11251 sodium is a potent, selective and orally activeendothelin A receptor ETA antagonist with an IC50 of 1.4 nM and a Ki of 0.43 nM. Sitaxsentan sodium exhibits an IC50 for the ETB receptor of as high as 9800 nM. Sitaxsentan sodium inhibits ET-1-induced phosphoinositide turnover. Sitaxsentan sodium can significantly alleviate pulmonary arterial hypertension PAH symptoms. Sitaxsentan sodium can be used for the study of PAH.
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