GENERAL CATALOGUE
SJL2-1
HY-174908 · 50 mg
MedChemExpress · Cat: HY-174908
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Manufacturer product page
medchemexpress.com/sjl2-1.htmlCatalog No: HY-174908
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
SJL2-1 is a PRMT5 inhibitor, with an IC50 of 1.56 ?M. SJL2-1 suppresses proliferation, migration, and invasion in prostate cancer cells. SJL2-1 promotes apoptosis and blocks the cell cycle at the G0/G1 phase. SJL2-1 can target the binding of PRMT5 in cells and inhibit the methylation and expression of the androgen receptor. SJL2-1 can be used for the study of early androgen-sensitive prostate cancer and advanced castration-resistant prostate cancer CRPC .
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