GENERAL CATALOGUE
SK-3-91
HY-137341 · 5 mg
MedChemExpress · Cat: HY-137341
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medchemexpress.com/sk-3-91.htmlCatalog No: HY-137341
CAS No: 2769753-23-1
Category: Epigenetics
Pack Size: 5 mg
Brand: MedChemExpress
Description
SK-3-91 is a PROTAC-type multi-kinase degrader that can jointly induce the degradation of the largest number of unique kinases more than 125 unique kinases . SK-3-91 induces protein degradation through the ubiquitin biotinylation E-STUB pathway. SK-3-91 degrades YTHDF2. SK-3-91 inhibits cell proliferation and induces morphological changes. Pink: TAE648 ligand HY-169396 ; Blue: E3 ligase ligand HY-131717 ; Black: Linker HY-140819 . The E3 ligase ligand and linker can form a conjugate HY-169397 .
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