GENERAL CATALOGUE
SK-575-NEG
HY-147101 · 5 mg
MedChemExpress · Cat: HY-147101
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medchemexpress.com/sk-575-neg.htmlCatalog No: HY-147101
CAS No: 2523017-04-9
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
SK-575-NEG compound 28 , a methylation counterpart of SK-575, is synthesized by methylation of the amino group of piperidine-2,6-dione in SK-575 as an control compound. SK-575-NEG is strongly bound to PARP1, with an IC50 of 2.64 nM. SK-575-NEG was completely ineffective in inducing PARP1 degradation in MDA-MB-436 and Capan-1 cells at concentrations up to 1 ?M.
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