GENERAL CATALOGUE
SK1-I
HY-119016 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-119016
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Catalog No: HY-119016
CAS No: 1072443-89-0
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SK1-I BML-258 , an analog of sphingosine, is an isozyme-specific competitive SPHK1 inhibitor with a Ki value of 10 ?M. SK1-I shows no activity at SPHK1 PKC?, PKC?, PKA, AKT1, ERK1, EGFR, CDK2, IKK? or CamK2?. SK1-I enhances autophagy and has antitumor activity.