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SK2188
GENERAL CATALOGUE

SK2188

HY-171767 · 1 mg

MedChemExpress · Cat: HY-171767

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medchemexpress.com/sk2188.html
Catalog No: HY-171767
CAS No: 3038446-94-2
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress

Description

SK2188 is a highly efficient and selective PROTAC degrader targeting AURKA DC50 = 3.9 nM . SK2188 induces DNA damage and cell apoptosis. SK2188 indirectly degrades MYCN, inhibits tumor cell proliferation, and provides insights into the study of MYCN-amplified neuroblastoma Pink: AURKA ligand: MK-5108 HY-13252 ; Blue: Thalidomide HY-14658 ; Black: Linker: Amino-PEG4-alcohol HY-W008005 .

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