GENERAL CATALOGUE
SKF-83566
HY-103430A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-103430A
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Manufacturer product page
medchemexpress.com/skf-83566.htmlCatalog No: HY-103430A
CAS No: 99295-33-7
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SKF-83566 is a potent, blood-brain permeable and orally active D1-like dopamine receptor D1DR antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor Ki=11 nM . SKF-83566 is a competitive DAT dopamine transporter inhibitor with an IC50 of 5.7 ?M. SKF-83566 also shows selective inhibition for adenylyl cyclase 2 AC2 over AC1 and AC5 in the isolated rabbit thoracic aorta. SKF-83566 can be used for research of parkinsonAAasAasAas disease and nicotine craving alleviation.
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