GENERAL CATALOGUE
SKF-96365 hydrochloride
HY-100001 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-100001
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Manufacturer product page
medchemexpress.com/SKF-96365-hydrochloride.htmlCatalog No: HY-100001
CAS No: 130495-35-1
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca2+ entry SOCE inhibitor. SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1, hKir2.1 and hKv4.3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells.
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