GENERAL CATALOGUE
SKI-II
BML-EI406 · 10 mg
Enzo · Cat: BML-EI406
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enzo.com/product/ski-ii/
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Catalog No: BML-EI406
CAS No: 312636-16-1
Category: Biochemicals
Pack Size: 10 mg
Brand: Enzo
Description
Selective, non-ATP competitive inhibitor of sphingosine kinase IC50= 0.5muM GST-hSK; IC50= 1.1muM intact JC mouse mammary adenovirus carcinoma cells showing no inhibition of hERK2, hPI3k and hPKCalpha at concentrations up to 60muM.Cytotoxic effects have been demonstrated against various tumor cell lines including some overexpressing P-glycoprotein or MRP1 T24, IC50= 4.6muM; MCF-7, IC50= 1.2muM; NCI/ADR, IC50= 1.3muM, MCRF-7/VP, IC50= 0.9muM
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