

HY-147949 · 50 mg
MedChemExpress · Cat: HY-147949
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medchemexpress.com/sklb0565.htmlDescription
SKLB0565 is a potent tubulin inhibitor. SKLB0565 shows significant anti-proliferative activity against CRC colorectal carcinoma cell lines, with IC50 values ranging from 0.012 ?M to 0.081 ?M. SKLB0565 causes G2/M phase arrest and mitochondria-mediated intrinsic apoptosis. SKLB0565 inhibits cell migration and disrupted the tube formation of HUVECs.







