GENERAL CATALOGUE
SLMP53-2
HY-153202 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-153202
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Catalog No: HY-153202
CAS No: 1826116-38-4
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SLMP53-2 is a mutant p53 reactivator. SLMP53-2 restores wild-type-like conformation and DNA-binding ability of mutp53-Y220C by enhancing its interaction with the Hsp70, leading to the reestablishment of p53 transcriptional activity. SLMP53-2 can induce cell cycle arrest, apoptosis and endoplasmic reticulum ER stress. SLMP53-2 exhibits antitumor activity.
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