GENERAL CATALOGUE
SLW131
HY-173052 · 50 mg
MedChemExpress · Cat: HY-173052
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medchemexpress.com/slw131.htmlCatalog No: HY-173052
CAS No: 681511-84-2
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
SLW131 Compound 10 is the antagonist for CCR7 with a good affinity of Ki of 9.85 nM. SLW131 inhibits CCL19-induced Go protein activation with an IC50 of 29.4 ?M, inhibits ?-arrestin2 recruitment with an IC50 of 6.0 ?M. SLW131 inhibits CCL19-induced cell morphological changes in primary BMDCs, and CCR7-mediated migration in mouse CD4+ T cell.
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