

HY-174229 · 50 mg
MedChemExpress · Cat: HY-174229
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medchemexpress.com/sm311.htmlDescription
SM311 Compound 10 , a chemical probe, is a potent selective irreversible LIMK1 inhibitor EC50=0.045 ?M, 30-fold selective over LIMK2. SM311 blocks cofilin phosphorylation and actin cytoskeleton regulation. SM311 is promising for research of neurodegenerative diseases like Fragile X syndrome FXS and AlzheimerAAasAasAas disease, as well as tumor invasion.





