GENERAL CATALOGUE
SMA-12b
HY-137007 · 1 mg
MedChemExpress · Cat: HY-137007
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medchemexpress.com/sma-12b.htmlCatalog No: HY-137007
CAS No: 1496553-39-9
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
SMA-12b is a small molecule analogue of the parasitic worm compound ES-62. SMA-12b has immunomodulatory activity, acting by regulating the expression of multiple inflammatory response genes, especially those associated with inflammatory bodies. SMA-12b significantly reduces the expression of cytokine IL-1? associated with inflammatory bodies and inhibites the production of IL-1? through a mechanism mediated by NRF2. SMA-12b can be used in the study of rheumatoid arthritis RA and other autoimmune diseases.
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