SMAD4 Mouse Monoclonal Antibody

Description

EnkiLife offers the SMAD4 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB,IHC,ICC,ELISA,FC application. Alternative Names of Immunogen: JIP; DPC4; MADH4; SMAD4. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily; SMAD4 is the common SMAD (co-SMAD). Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. May act as a tumor suppressor Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. Research Area: TGF-beta signaling pathway