SMAD5 Mouse Monoclonal Antibody

Description

EnkiLife offers the SMAD5 Mouse Monoclonal Antibody. This antibody reacts with Human,Rat species and is suitable for WB,IHC,ICC,ELISA,FC application. Alternative Names of Immunogen: Dwfc; JV5-1; MADH5; DKFZp781C1895; DKFZp781O1323; SMAD5. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo; lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous. Research Area: TGF-beta signaling pathway