GENERAL CATALOGUE
SMCypI C31
HY-125182 · 50 mg
MedChemExpress · Cat: HY-125182
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medchemexpress.com/smcypi-c31.htmlCatalog No: HY-125182
CAS No: 2649904-85-6
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
SMCypI C31 is a non-peptidic cyclophilin inhibitor with potent peptidyl-prolyl cis/trans isomerases PPIase inhibitory activity IC50 of 0.1 AAasAasAAmuM . SMCypI C31 shows pangenotype anti-HCV activity with EC50s ranging from 1.20 to 7.76 ?M for genotype 1a, 1b, 2a, 3a, and 5a HCV subgenomic replicons HCV-SGRs and chimeric genotype 2a/4a HCV-SGRs. SMCypI C31 disrupts the cyclophilin A-NS5A interaction.
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