GENERAL CATALOGUE
SMD-1087
HY-170828 · 50 mg
MedChemExpress · Cat: HY-170828
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medchemexpress.com/smd-1087.htmlCatalog No: HY-170828
CAS No: 3033586-04-5
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
SMD-1087 is a PROTAC that selectively targets SMARCA2 DC50=8 nM, Dmax=89 % and SMARCA4 with a DC50 of 1 ?M. SMD-1087 consists of the E3 ligase ligand S,R,S -AHPC-Me blue part HY-112078 , the target protein ligand SMI-1074 red part HY-170817 , and the PROTAC linker 1r,4r -tert-Butyl 4- bromomethyl cyclohexanecarboxylate black part HY-W890392 . Among them, its target protein ligand + Linker part corresponds to SMARCA2 Ligand-Linker Conjugate-1 HY-170829 .
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