

A04205 · 50 uL
GenScript · Cat: A04205
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Manufacturer product page
genscript.com/antibody/A04205-SMURF2_Antibody_mAb_Rabbit.htm...
Description
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.Interacts with SMAD7 to trigger SMAD7-mediated transforming growth factor beta/TGF-beta receptor ubiquitin-dependent degradation, thereby down-regulating TGF-beta signaling.





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