SOCS3 Mouse Monoclonal Antibody

Description

EnkiLife offers the SOCS3 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ICC,ELISA,FC application. Alternative Names of Immunogen: CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. Research Area: Jak-STAT signaling pathway