GENERAL CATALOGUE
SOS1-IN-18
HY-172221 · 50 mg
MedChemExpress · Cat: HY-172221
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medchemexpress.com/sos1-in-18.html
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Catalog No: HY-172221
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
SOS1-IN-18 Compound 8 is the inhibitor for Son of Sevenless 1 protein SOS1 with a KD of 2.6 nM, and inhibits SOS1-KRAS G12C interaction with an IC50 of 3.4 nM. SOS1-IN-18 inhibits the phosphorylation of ERK in H358 with an IC50 of 31 nM, inhibits the proliferation of H358 with an IC50 of 5 nM.
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