GENERAL CATALOGUE
Sotorasib-d7
HY-114277S · 1 mg
MedChemExpress · Cat: HY-114277S
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Catalog No: HY-114277S
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
Sotorasib-d7 AMG-510-d7 is a deuterium-labeled Sotorasib HY-114277 . Sotorasib AMG-510 is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib leads to the regression of KRAS G12C?mutated locally advanced or metastatic non?small cell lung cancer NSCLC .
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