GENERAL CATALOGUE
Sparfosic acid
HY-112732 · 1 mg
MedChemExpress · Cat: HY-112732
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Catalog No: HY-112732
CAS No: 51321-79-0
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
Sparfosic acid, a DNA antimetabolite agent, is a potent inhibitor of aspartate transcarbamoyl transferase, the enzyme catalyzing the second step of de novo pyrimidine biosynthesis. Sparfosic acid synergistically enhances the cytotoxicity of a combination of 5-fluorouracil 5-FU and interferon-alpha IFN against human colon cancer cell lines.
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