GENERAL CATALOGUE
Spiclomazine
HY-154313 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-154313
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Catalog No: HY-154313
CAS No: 24527-27-3
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Spiclomazine Clospirazine is a potent mutant KRAS G12C inhibitor that selectively inhibits mutant KRAS-driven pancreatic cancer. Spiclomazine can eliminate KRas-GTP levels in KRAS-driven pancreatic cancer and effectively inhibit RAS-mediated signaling. Spiclomazine significantly inhibits tumor progression in mouse renal capsule xenotransplantation models.