GENERAL CATALOGUE
Spliceostatin A
HY-16466 · 1 mg
MedChemExpress · Cat: HY-16466
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Manufacturer product page
medchemexpress.com/spliceostatin-a.htmlCatalog No: HY-16466
CAS No: 391611-36-2
Category: Epigenetics
Pack Size: 1 mg
Brand: MedChemExpress
Description
Spliceostatin A, the FR901464 HY-16212 methylated derivative, is a potent anti-tumor agent. Spliceostatin A inhibits splicing and promotes pre-mRNA accumulation by binding SF3B1. SF3B1 is a subcomplex of U2 small nuclear ribonucleoprotein in the spliceosome. Spliceostatin A induces Apoptosis in chronic lymphocytic leukemia CLL cells.
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