SPP1 Mouse Monoclonal Antibody

Description

EnkiLife offers the SPP1 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for IHC,ELISA application. Alternative Names of Immunogen: OPN; BNSP; BSPI; ETA-1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:200-1:400,ELISA 1:5000-1:20000 Background: The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. Research Area: PI3K-Akt signaling pathway