SQSTM1 Mouse Monoclonal Antibody

Description

EnkiLife offers the SQSTM1 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat,Rabbit,Monkey species and is suitable for WB,IHC,ICC,ELISA,FC application. Alternative Names of Immunogen: p60; p62; A170; OSIL; PDB3; ZIP3; p62B. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:100-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. Research Area: Autophagy,Apoptosis