GENERAL CATALOGUE
SR 142948 dihydrochloride
HY-107664A · 1 mg
MedChemExpress · Cat: HY-107664A
₹130 – ₹190 approx.This price excludes freight and taxes. Please RFQ to get the final price.
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/sr-142948-dihydrochloride.htmlCatalog No: HY-107664A
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
SR 142948 dihydrochloride is an orally active and selective non-peptide neurotensin receptor NT antagonist with IC50s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 dihydrochloride antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC50 of 3.9 nM. SR 142948 dihydrochloride blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 dihydrochloride shows blood-brain permeability and can be used in study of psychiatric disorders.
More from MedChemExpress
GPR120 Agonist 1
HY-108711
GPCR G Protein
AG-045572
HY-107534
GPCR G Protein
Pamabrom
HY-17391
GPCR G Protein
ZD-7114
HY-101320
GPCR G Protein
Vasopressin Dimer (anti-parallel) (TFA)
HY-P5214
GPCR G Protein
Zimeldine-d6
HY-118835S
GPCR G Protein
ZM241385 (Standard)
HY-19532R
GPCR G Protein
(5S,6S)-DiHETE
HY-130138
GPCR G Protein