GENERAL CATALOGUE
SR-4835
HY-130250 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-130250
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Manufacturer product page
medchemexpress.com/sr-4835.htmlCatalog No: HY-130250
CAS No: 2387704-62-1
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM . SR-4835 acts in synergy with DNA-damaging chemotherapy and PARP inhibitors and provokes triple-negative breast cancer TNBC cell death.
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