GENERAL CATALOGUE
SSE1806
HY-156088 · 1 mg
MedChemExpress · Cat: HY-156088
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Catalog No: HY-156088
CAS No: 3053861-26-7
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
SSE1806 is a derivative of podophyllotoxin a natural antimitotic agent and a microtubule/tubulin inhibitor with significant anticancer and antiproliferative activities. The GI50 of SSE1806 on cancer cell growth ranges from 1.29-21.15 ?M. SSE1806 causes mitotic abnormalities and G2/M phase arrest, increases p53 expression, and inhibits colon cancer organoid growth. SSE1806 is able to overcome multidrug resistance in cell lines overexpressing MDR-1.
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