GENERAL CATALOGUE
SSO111 sodium
HY-158828 · 50 mg
MedChemExpress · Cat: HY-158828
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medchemexpress.com/sso111-sodium.html
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Catalog No: HY-158828
Category: JAK STAT Signaling
Pack Size: 50 mg
Brand: MedChemExpress
Description
SSO111 sodium, a 20mer fully modified antisense oligonucleotide, targets the oncogene?HER2. SSO111 sodium induces exon 15 skipping during splicing, leading to the generation of a novel mRNA transcript that excludes exon 15. SSO111 sodium downregulated HER2 mRNA, which resulted in the inhibition of proliferation and induction of apoptosis in HER2-overexpressing tumor cells.
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