GENERAL CATALOGUE
SST0116CL1
HY-164399 · 50 mg
MedChemExpress · Cat: HY-164399
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medchemexpress.com/sst0116cl1.htmlCatalog No: HY-164399
CAS No: 1799802-29-1
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
SST0116CL1 is a HSP90 inhibitor IC50: 0.21 ?M . SST0116CL1 binds to the ATP binding pocket of Hsp90, and interferes with Hsp90 chaperone function thus resulting in client protein EGFR, CDK4 and AKT degradation. SST0116CL1 induces degradation of Her2 in BT-474 cell IC50: 0.2 ?M . SST0116CL1 has antiproliferative activity and inhibits tumor growth. SST0116CL1 can be used for the study of leukemia, gastric and ovarian carcinoma.
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