GENERAL CATALOGUE
ST-CY14
HY-P10873 · 50 mg
MedChemExpress · Cat: HY-P10873
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medchemexpress.com/st-cy14.html
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Catalog No: HY-P10873
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
ST-CY14 is an inhibitor for Nur77-PPAR? interaction with an EC50 of 3.15 ?M, that binds to Nur77 Kd=32 nM , blocks Nur77 from being ubiquitinated and degraded by PPAR?, reduces fatty acid uptake and mitochondrial respiration, and inhibits the transcription of CD36 and FABP4. ST-CY14 inhibits the proliferation and migration of cancer cell MCF7 and MDA-MB-231. ST-CY14 inhibits tumor growth and bone metastasis in mouse models.
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