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ST6GAL1-IN-1
GENERAL CATALOGUE

ST6GAL1-IN-1

HY-173496 · 5 mg

MedChemExpress · Cat: HY-173496

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Manufacturer product page

medchemexpress.com/st6gal1-in-1.html
Catalog No: HY-173496
CAS No: 192876-13-4
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress

Description

ST6GAL1-IN-1 is an orally active selective ST6GAL1 inhibitor IC50 = 20 ?M . ST6GAL1-IN-1 exhibits high antimetastatic potential, effectively inhibiting the migration of MDA-MB-231 cells at noncytotoxic concentrations. ST6GAL1-IN-1 can disrupt integrin sialylation in MDA-MB-231 cells. ST6GAL1-IN-1 inhibits tumor angiogenesis and cancer metastasis via the Integrin/VEGFR2-mediated signaling pathway. ST6GAL1-IN-1 effectively suppresses both tumor growth and cancer metastasis on the MDA-MB-231 xenograft model. ST6GAL1-IN-1 can be used for the study of Triple-negative breast cancer TNBC .

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