Stable CYP24A1 Expressing LS180 Cell Line

Name: Stable CYP24A1 Expressing LS180 Cell Line
Brand: abm good

T6112 · 1 x 106 cells / 1.0 mL

abm good · Cat: T6112

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Catalog No: T6112

Category: Cellular Materials

Pack Size: 1 x 106 cells / 1.0 mL

Brand: abm good

Description

Human Caucasian colon adenocarcinoma cell line LS 180 was transfected with reporter plasmid CYP24minP-pNL2.1 Nluc/Hygro to generate Stable CYP24A1 Expressing LS180 Cell Line. Stable CYP24A1 Expressing LS180 Cell Line contains much of the CYP24A1 promoter and therefore, can be used for study of transcriptional regulation of CYP24A1. This cell line allows for measurement of Vitamin D receptor transcriptional activity. This cell line can be used to profile VDR transcriptional activity in response to analogues of vitamin D, and intermediates in vitamin D2 and vitamin D3 metabolic pathways.