Stable HEK293 Expressing Rpn11-HTBH Cell Line

Name: Stable HEK293 Expressing Rpn11-HTBH Cell Line
Brand: abm good

T6007 · 1 x 106 cells / 1.0 mL

abm good · Cat: T6007

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Catalog No: T6007

Category: Cellular Materials

Pack Size: 1 x 106 cells / 1.0 mL

Brand: abm good

Description

Stable HEK293 Expressing Rpn11-HTBH Cell Line was generated through infecting HEK293 cells with retrovirus carrying the pQCXIP-hRpn11-HTBH. Human Rpn11, or the 26S proteasome regulatory subunit rpn11, is the essential deubiquitinase DUB of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. HTBH-tag on the C-terminus of the non-ATPase subunit of the human Rpn11 allows for the effective and rapid isolation and purification of the human 26S proteasome complex.