GENERAL CATALOGUE
STAMBP-IN-1
HY-141852 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-141852
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Manufacturer product page
medchemexpress.com/stambp-in-1.htmlCatalog No: HY-141852
CAS No: 896683-78-6
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
STAMBP-IN-1 is a small-molecule inhibitor of STAMBP deubiquitinase, and interrupts STAMBP-Ub-NALP7 interaction. STAMBP-IN-1 decreases protein level of its inflammasome substrate NALP7 and suppresses IL-1b release after Toll-like receptor TLR agonism. STAMBP-IN-1 inhibits the activity of STAMBP to cleave recombinant di-Ub with an IC50 value of 0.33 mM.
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