GENERAL CATALOGUE
Stapokibart
HY-P990093 · 1 mg
MedChemExpress · Cat: HY-P990093
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medchemexpress.com/stapokibart.htmlCatalog No: HY-P990093
CAS No: 2734715-10-5
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
Stapokibart CM310 is a humanized monoclonal antibody targeting IL-4R? KD values of 0.25 nM, 1.50 nM, and 2.75 nM for human, cynomolgus monkey, and rat IL-4R?, respectively . Stapokibart effectively blocks the interaction of cytokines IL-4 and IL-13 with their co-receptor subunit IL-4R?. Stapokibart reduces IL-4 and IL-13 mRNA, inhibits CD23 upregulation, and inhibits IL-4 and IL-13-induced STAT6 activation. Stapokibart improves inflammation airway inflammation, rhinitis, dermatitis .
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