GENERAL CATALOGUE
STAT-3/c-Src-IN-1
HY-175298 · 50 mg
MedChemExpress · Cat: HY-175298
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medchemexpress.com/stat-3-c-src-in-1.html
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Catalog No: HY-175298
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
STAT-3/c-Src-IN-1 Compound 12d is a dual STAT-3 IC50=0.844 ?M and c-Src IC50=0.268 ?M inhibitor. STAT-3/c-Src-IN-1 blocks tumor cell proliferation, migration, and angiogenesis signaling pathways. STAT-3/c-Src-IN-1 exhibits potent anti-proliferative activity against melanoma SK-MEL-2 and CNS cancer SNB-75 cell lines GI50=-5.75 ?M and -5.63 ?M , inducing tumor cell apoptosis via G0/G1 and G2/M phase cell cycle arrest. STAT-3/c-Src-IN-1 is promising for research of melanoma and glioblastoma.
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